Welcome,

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It is my pleasure to welcome you to the 23rd Annual World Congress on Insulin Resistance, Diabetes and Cardiovascular Disease (WCIRDC): Exploring New Frontiers in Metabolism—Tomorrow’s Clinical Science Today. 

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The 23rd Annual WCIRDC will be held on December 3-6, 2025, at the Hilton Universal City, Los Angeles, California. This CME/MOC conference will be available On-Demand for 90 days following the meeting.

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WCIRDC is world’s premier conference on cardiorenal and metabolic diseases, it is the only meeting of its size to combine basic science and clinical research in a cross-discipline format that promotes communication between researchers, clinicians, and other healthcare professionals. 

The world-renowned expert faculty and attendees engage with each other in in-depth discussions on the inter-related pathophysiologies and clinical manifestations of insulin resistance, diabetes, obesity, lipid disorders, cardiovascular disease (CVD), chronic kidney disease (CKD), fatty liver- MASLD/MASH and other cardiorenal and metabolic diseases. Sessions are designed to explore how basic and preclinical research findings relate to clinical trial findings and the impact on best practices in the cardiometabolism. The WCIRDC faculty consists of globally acclaimed experts who link research to clinical practice in a bench-to-bedside-to-bench approach which is unique to this state-of-the-art program. 

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We are proud to honor Tracey L. McLaughlin, MD, MS Professor of Medicine Stanford, with the prestigious "Gerald Reaven Distinguished Leader in Insulin Resistance" Award, recognizing her leadership and exceptional contributions to the field. Dr McLaughlin’s keynote lecture will be: Adipocyte Dysfunction and the Metabolic Heterogeneity of Obesity. 
   
This year’s conference will cover a wide range of topics addressing obesity, liver disease, atherosclerosis cardiovascular disease, digital health and AI, the incretins phenomenon, cardiomyopathy & heart failure, kidney disease, a glimpse into the future, what’s in the pipeline, and much more encompassing the multifaceted realm of metabolic medicine. Distinguished experts are poised to unveil groundbreaking perspectives fostering an environment conducive to collaborative learning and professional growth.

Clinical workshops & meet-the-expert small groups sessions will provide attendees with a rare opportunity to personally interact with esteemed leaders in an intimate setting. 

The Congress has a strong and highly successful abstracts program. Abstracts will be published in the journal Metabolism Clinical and Experimental zImpact factor 11.96– Editor in Chief: Christos S. Mantzoros, MD, DSc, PhD. 

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The 23rd  WCIRDC will feature a robust poster hall, oral abstract presentations, an impressive exhibit hall, and industry supported non-CME programs featuring important new scientific concepts with some of the world’s best-known educators.

I look forward to you attending this exciting conference on December 3-6, 2025, at Hilton Universal City Los Angeles, California.  We hope to see you there.  

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Best regards, 

 
Yehuda Handelsman, MD
Chair & Program Director

 

 

 

 

 

 

 

 

 

 

Scientific Organizing Committee – International Committee for Insulin Resistance (ICIR)
 
Yehuda Handelsman, MD Chair
Tarzana, CA

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Richard N. Bergman, PhD
Los Angeles, CA

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Zachary T. Bloomgarden, MD
New York, NY

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Matthew J. Budoff, MD
Los Angeles, CA

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Sonia Caprio, MD
New Haven, CT

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Robert J. Chilton, DO
San Antonio, TX

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Jaime A. Davidson, MD
Dallas, TX

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Ralph A. DeFronzo, MD
San Antonio, TX

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Brian J. Feldman, MD

New Haven, CT

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Vivian A. Fonseca, MD
New Orleans, LA

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W. Timothy Garvey, MD
Birmingham, AL

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Peter J. Grant, MD
Leeds, United Kingdom

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Jennifer B. Green, MD
Durham, NC

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Stephen J. Greene, MD
Durham, NC

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George Grunberger, MD
Bloomfield Hills, MI

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Chris K. Guerin, MD
Oceanside, CA

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Josephine Harrington, MD

Durham, NC

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Ania M. Jastreboff, MD, PhD
New Haven, CT

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Paul S. Jellinger, MD
Hollywood, FL

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Samuel Klein, MD
St. Louis, MO

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Ronald M. Krauss, MD

San Francisco, CA​

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Rohit N. Kulkarni, MD

Cambridge, MA

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Norman E. Lepor. MD
Los Angeles, CA

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Derek LeRoith, MD, PhD
New York, NY

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Philip Levy, MD
Phoenix, AZ

Ildiko Lingvay, MD, MPH, MSCS
Dallas, Texas

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Rohit Loomba, MD, MHSc

 San Diego, CA

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Christos S. Mantzoros, MD, PhD
Boston, MA

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Seth S. Martin, MD

Baltimore, MD

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Nikolaus Marx, MD
Aachen, Germany

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Tracey L. McLaughlin, MD
Stanford, CA

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Christian W. Mende, MD
La Jolla, CA

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Erin D. Michos, MD, MHS
Baltimore, MD

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Jorge Plutzky, MD
Boston, MA

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Richard E. Pratley, MD
Orlando, FL

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Peter Rossing, MD

Herlev, Denmark

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Elizabeth Selvin, PhD, MPH

Baltimore, MD​

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Philipp E. Scherer, PhD
Dallas, TX

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Viral N. Shah, MD

​Indianapolis, IN 

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Bart Staels, PhD
Lille, France
 

Pam R. Taub, MD
San Diego, CA

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Muthiah Vaduganathan, MD, MPH
Boston, MA

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Matthew R. Weir, MD
Baltimore, MD

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Paul Zimmet, AO, PhD
Melbourne, Australia